Davoren, Jennifer E <br/><br/>
Discovery of the Potent and Selective M1 PAM-Agonist N-[(3R,4S)-3-Hydroxytetrahydro-2H-pyran-4-yl]-5-methyl-4-[4-(1,3-thiazol-4-yl)benzyl]pyridine-2-carboxamide (PF-06767832): Evaluation of Efficacy and Cholinergic Side Effects.  [electronic resource] 

 -  Journal of medicinal chemistry  07 2016 
 - 6313-28 p.  digital 
<br/><br/> Publication Type: Journal Article 
<br/><br/><label>ISSN: </label>1520-4804 
<br/><br/><label>Standard No.: </label>10.1021/acs.jmedchem.6b00544  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Animals<br/>Dose-Response Relationship, Drug<br/>Drug Discovery<br/>Female<br/>Male<br/>Mice<br/>Models, Molecular<br/>Molecular Structure<br/>Picolinic Acids--chemical synthesis<br/>Rats<br/>Receptor, Muscarinic M1--agonists<br/>Structure-Activity Relationship<br/>Thiazoles--chemical synthesis