TY - GEN AU - Brunen,Diede AU - García-Barchino,María José AU - Malani,Disha AU - Jagalur Basheer,Noorjahan AU - Lieftink,Cor AU - Beijersbergen,Roderick L AU - Murumägi,Astrid AU - Porkka,Kimmo AU - Wolf,Maija AU - Zwaan,C Michel AU - Fornerod,Maarten AU - Kallioniemi,Olli AU - Martínez-Climent,José Ángel AU - Bernards,René TI - Intrinsic resistance to PIM kinase inhibition in AML through p38α-mediated feedback activation of mTOR signaling SN - 1949-2553 PY - 2018///0202 KW - Animals KW - Cell Line, Tumor KW - Cell Proliferation KW - drug effects KW - Humans KW - K562 Cells KW - Leukemia, Myeloid, Acute KW - drug therapy KW - Male KW - Mice KW - Mice, Transgenic KW - Mitogen-Activated Protein Kinase 14 KW - antagonists & inhibitors KW - Protein Kinase Inhibitors KW - pharmacology KW - Proto-Oncogene Proteins c-pim-1 KW - Signal Transduction KW - TOR Serine-Threonine Kinases KW - metabolism KW - Xenograft Model Antitumor Assays N1 - Publication Type: Journal Article UR - https://doi.org/10.18632/oncotarget.9822 ER -