Chromosome thripsis by DNA double strand break clusters causes enhanced cell lethality, chromosomal translocations and 53BP1-recruitment. [electronic resource]
- Nucleic acids research 09 2016
- 7673-90 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1362-4962
10.1093/nar/gkw487 doi
Animals CHO Cells Cell Death Chromosomes, Mammalian--metabolism Chromothripsis Clone Cells Cricetinae Cricetulus DNA Breaks, Double-Stranded DNA Repair Deoxyribonucleases, Type II Site-Specific--metabolism Genome Green Fluorescent Proteins--metabolism Metaphase Saccharomyces cerevisiae Proteins--metabolism Signal Transduction Translocation, Genetic Tumor Suppressor p53-Binding Protein 1--metabolism