GAPDH/Siah1 cascade is involved in traumatic spinal cord injury and could be attenuated by sivelestat sodium. [electronic resource]
- Neuroscience 08 2016
- 171-80 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1873-7544
10.1016/j.neuroscience.2016.05.054 doi
Active Transport, Cell Nucleus--drug effects Animals Apoptosis--drug effects Disease Models, Animal Drug Evaluation, Preclinical Glyceraldehyde-3-Phosphate Dehydrogenases--metabolism Glycine--analogs & derivatives Interleukin-1beta--metabolism Male NF-kappa B--metabolism Neuroprotective Agents--pharmacology Nitric Oxide Synthase Type II--metabolism Nuclear Proteins--metabolism Random Allocation Rats, Sprague-Dawley Recovery of Function--drug effects Signal Transduction--drug effects Spinal Cord--drug effects Spinal Cord Injuries--drug therapy Sulfonamides--pharmacology Tumor Necrosis Factor-alpha--metabolism Ubiquitin-Protein Ligases--metabolism Seven in Absentia Proteins