TY - GEN AU - Avery,Lindsay B AU - Wang,Mengmeng AU - Kavosi,Mania S AU - Joyce,Alison AU - Kurz,Jeffrey C AU - Fan,Yao-Yun AU - Dowty,Martin E AU - Zhang,Minlei AU - Zhang,Yiqun AU - Cheng,Aili AU - Hua,Fei AU - Jones,Hannah M AU - Neubert,Hendrik AU - Polzer,Robert J AU - O'Hara,Denise M TI - Utility of a human FcRn transgenic mouse model in drug discovery for early assessment and prediction of human pharmacokinetics of monoclonal antibodies SN - 1942-0870 PY - 2017///1206 KW - Animals KW - Antibodies, Monoclonal KW - administration & dosage KW - Chromatography, Liquid KW - Drug Discovery KW - methods KW - Hemizygote KW - Histocompatibility Antigens Class I KW - genetics KW - Homozygote KW - Humans KW - Macaca fascicularis KW - Mice KW - Mice, Inbred BALB C KW - Mice, Inbred C57BL KW - Mice, Transgenic KW - Models, Animal KW - Predictive Value of Tests KW - Receptors, Fc KW - Tandem Mass Spectrometry N1 - Publication Type: Journal Article UR - https://doi.org/10.1080/19420862.2016.1193660 ER -