TY  - GEN
AU  - Johansson,Catrine
AU  - Velupillai,Srikannathasan
AU  - Tumber,Anthony
AU  - Szykowska,Aleksandra
AU  - Hookway,Edward S
AU  - Nowak,Radoslaw P
AU  - Strain-Damerell,Claire
AU  - Gileadi,Carina
AU  - Philpott,Martin
AU  - Burgess-Brown,Nicola
AU  - Wu,Na
AU  - Kopec,Jola
AU  - Nuzzi,Andrea
AU  - Steuber,Holger
AU  - Egner,Ursula
AU  - Badock,Volker
AU  - Munro,Shonagh
AU  - LaThangue,Nicholas B
AU  - Westaway,Sue
AU  - Brown,Jack
AU  - Athanasou,Nick
AU  - Prinjha,Rab
AU  - Brennan,Paul E
AU  - Oppermann,Udo
TI  - Structural analysis of human KDM5B guides histone demethylase inhibitor development
SN  - 1552-4469
PY  - 2017///0515
KW  - Antineoplastic Agents
KW  - chemistry
KW  - Cell Proliferation
KW  - drug effects
KW  - Drug Screening Assays, Antitumor
KW  - Enzyme Inhibitors
KW  - Histone Demethylases
KW  - antagonists & inhibitors
KW  - Humans
KW  - Jumonji Domain-Containing Histone Demethylases
KW  - Models, Molecular
KW  - Multiple Myeloma
KW  - drug therapy
KW  - Nuclear Proteins
KW  - Protein Conformation
KW  - Repressor Proteins
KW  - Structure-Activity Relationship
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1038/nchembio.2087
ER  -