TY - GEN AU - Wang,Hong AU - Liu,Anna AU - Kuo,Yingyi AU - Chi,Eric AU - Yang,Xu AU - Zhang,Lanjing AU - Yang,Chung S TI - Obesity promotes PhIP-induced small intestinal carcinogenesis in hCYP1A-db/db mice: involvement of mutations and DNA hypermethylation of Apc SN - 1460-2180 PY - 2017///0519 KW - Adenomatous Polyposis Coli Protein KW - genetics KW - Animals KW - Carcinogenesis KW - drug effects KW - Cytochrome P-450 CYP1A1 KW - DNA Methylation KW - Humans KW - Imidazoles KW - toxicity KW - Intestinal Neoplasms KW - chemically induced KW - Intestine, Small KW - Male KW - Mice KW - Mice, Transgenic KW - Mutation KW - Neoplasm Proteins KW - biosynthesis KW - Obesity KW - complications KW - Receptors, Leptin KW - beta Catenin N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural UR - https://doi.org/10.1093/carcin/bgw054 ER -