TY - GEN AU - Ferraldeschi,Roberta AU - Welti,Jonathan AU - Powers,Marissa V AU - Yuan,Wei AU - Smyth,Tomoko AU - Seed,George AU - Riisnaes,Ruth AU - Hedayat,Somaieh AU - Wang,Hannah AU - Crespo,Mateus AU - Nava Rodrigues,Daniel AU - Figueiredo,Ines AU - Miranda,Susana AU - Carreira,Suzanne AU - Lyons,John F AU - Sharp,Swee AU - Plymate,Stephen R AU - Attard,Gerhardt AU - Wallis,Nicola AU - Workman,Paul AU - de Bono,Johann S TI - Second-Generation HSP90 Inhibitor Onalespib Blocks mRNA Splicing of Androgen Receptor Variant 7 in Prostate Cancer Cells SN - 1538-7445 PY - 2017///0724 KW - Animals KW - Benzamides KW - pharmacology KW - Blotting, Western KW - Cell Line, Tumor KW - Drug Resistance, Neoplasm KW - drug effects KW - HSP90 Heat-Shock Proteins KW - antagonists & inhibitors KW - Humans KW - Immunohistochemistry KW - Immunoprecipitation KW - Isoindoles KW - Male KW - Mice KW - Polymerase Chain Reaction KW - Prostatic Neoplasms KW - genetics KW - RNA Splicing KW - RNA, Messenger KW - Receptors, Androgen KW - Xenograft Model Antitumor Assays N1 - Publication Type: Journal Article UR - https://doi.org/10.1158/0008-5472.CAN-15-2186 ER -