TY  - GEN
AU  - Zhao,H
AU  - Lu,Z
AU  - Bauzon,F
AU  - Fu,H
AU  - Cui,J
AU  - Locker,J
AU  - Zhu,L
TI  - p27T187A knockin identifies Skp2/Cks1 pocket inhibitors for advanced prostate cancer
SN  - 1476-5594
PY  - 2017///0901
KW  - Animals
KW  - Apoptosis
KW  - genetics
KW  - CDC2-CDC28 Kinases
KW  - metabolism
KW  - Cell Line, Tumor
KW  - Cell Transformation, Neoplastic
KW  - Cyclin-Dependent Kinase Inhibitor p27
KW  - Disease Progression
KW  - E2F1 Transcription Factor
KW  - Gene Knock-In Techniques
KW  - Humans
KW  - Male
KW  - Mice
KW  - Mice, Knockout
KW  - Mice, Transgenic
KW  - Neoplasm Staging
KW  - Prostate
KW  - Prostatic Neoplasms
KW  - drug therapy
KW  - Retinoblastoma Protein
KW  - deficiency
KW  - S-Phase Kinase-Associated Proteins
KW  - Tumor Protein p73
KW  - Tumor Suppressor Protein p53
KW  - Ubiquitination
N1  - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1038/onc.2016.175
ER  -