Nathwani, Seema-Maria <br/><br/>
The pyrrolo-1,5-benzoxazepine, PBOX-15, enhances TRAIL‑induced apoptosis by upregulation of DR5 and downregulation of core cell survival proteins in acute lymphoblastic leukaemia cells.  [electronic resource] 

 -  International journal of oncology  Jul 2016 
 - 74-88 p.  digital 
<br/><br/> Publication Type: Journal Article 
<br/><br/><label>ISSN: </label>1791-2423 
<br/><br/><label>Standard No.: </label>10.3892/ijo.2016.3518  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Apoptosis--drug effects<br/>CASP8 and FADD-Like Apoptosis Regulating Protein--biosynthesis<br/>Caspase 8--biosynthesis<br/>Cell Line, Tumor<br/>Drug Resistance, Neoplasm--genetics<br/>Drug Synergism<br/>Gene Expression Regulation, Leukemic--drug effects<br/>Humans<br/>Myeloid Cell Leukemia Sequence 1 Protein--biosynthesis<br/>Oxazepines--administration & dosage<br/>Phosphatidylinositol 3-Kinases--genetics<br/>Precursor Cell Lymphoblastic Leukemia-Lymphoma--drug therapy<br/>Pyrroles--administration & dosage<br/>Receptors, TNF-Related Apoptosis-Inducing Ligand--biosynthesis<br/>Signal Transduction--drug effects<br/>TNF-Related Apoptosis-Inducing Ligand--administration & dosage