TY - GEN AU - Ha,S H AU - Ferrell,J E TI - Thresholds and ultrasensitivity from negative cooperativity SN - 1095-9203 PY - 2016///0718 KW - DNA KW - chemistry KW - Ligands KW - Models, Molecular KW - Multiprotein Complexes KW - Protein Binding KW - Protein Multimerization KW - Receptors, Cell Surface KW - Signal Transduction N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1126/science.aad5937 ER -