Zhao, Jianyun

Inhibition of CHK1 enhances cell death induced by the Bcl-2-selective inhibitor ABT-199 in acute myeloid leukemia cells. [electronic resource] - Oncotarget Jun 2016 - 34785-99 p. digital

Publication Type: Journal Article

1949-2553

10.18632/oncotarget.9185 doi


Antineoplastic Agents--pharmacology
Antineoplastic Combined Chemotherapy Protocols--pharmacology
Apoptosis--drug effects
Bridged Bicyclo Compounds, Heterocyclic--pharmacology
Cell Line, Tumor
Checkpoint Kinase 1--antagonists & inhibitors
DNA Damage--drug effects
Drug Resistance, Neoplasm
Drug Synergism
G2 Phase Cell Cycle Checkpoints--drug effects
HL-60 Cells
Humans
Leukemia, Myeloid, Acute--drug therapy
Mitosis--drug effects
Myeloid Cell Leukemia Sequence 1 Protein--metabolism
Phenylurea Compounds--pharmacology
Proto-Oncogene Proteins c-bcl-2--antagonists & inhibitors
Pyrazines--pharmacology
Sulfonamides--pharmacology
THP-1 Cells
U937 Cells