Zhao, Jianyun
Inhibition of CHK1 enhances cell death induced by the Bcl-2-selective inhibitor ABT-199 in acute myeloid leukemia cells. [electronic resource]
- Oncotarget Jun 2016
- 34785-99 p. digital
Publication Type: Journal Article
ISSN: 1949-2553
Standard No.: 10.18632/oncotarget.9185 doi
Subjects--Topical Terms: Antineoplastic Agents--pharmacology Antineoplastic Combined Chemotherapy Protocols--pharmacology Apoptosis--drug effects Bridged Bicyclo Compounds, Heterocyclic--pharmacology Cell Line, Tumor Checkpoint Kinase 1--antagonists & inhibitors DNA Damage--drug effects Drug Resistance, Neoplasm Drug Synergism G2 Phase Cell Cycle Checkpoints--drug effects HL-60 Cells Humans Leukemia, Myeloid, Acute--drug therapy Mitosis--drug effects Myeloid Cell Leukemia Sequence 1 Protein--metabolism Phenylurea Compounds--pharmacology Proto-Oncogene Proteins c-bcl-2--antagonists & inhibitors Pyrazines--pharmacology Sulfonamides--pharmacology THP-1 Cells U937 Cells