TY  - GEN
AU  - Lock,Rebecca
AU  - Ingraham,Rachel
AU  - Maertens,Ophélia
AU  - Miller,Abigail L
AU  - Weledji,Nelly
AU  - Legius,Eric
AU  - Konicek,Bruce M
AU  - Yan,Sau-Chi B
AU  - Graff,Jeremy R
AU  - Cichowski,Karen
TI  - Cotargeting MNK and MEK kinases induces the regression of NF1-mutant cancers
SN  - 1558-8238
PY  - 2017///0913
KW  - Anilides
KW  - administration & dosage
KW  - Animals
KW  - Cell Line, Tumor
KW  - Genes, Neurofibromatosis 1
KW  - Humans
KW  - MAP Kinase Kinase Kinases
KW  - antagonists & inhibitors
KW  - Mechanistic Target of Rapamycin Complex 1
KW  - Mice
KW  - Multiprotein Complexes
KW  - metabolism
KW  - Mutation
KW  - Nerve Sheath Neoplasms
KW  - drug therapy
KW  - Neurofibromin 1
KW  - genetics
KW  - Nucleocytoplasmic Transport Proteins
KW  - Phosphorylation
KW  - Protein Kinase Inhibitors
KW  - Protein Serine-Threonine Kinases
KW  - Pyridines
KW  - Signal Transduction
KW  - TOR Serine-Threonine Kinases
N1  - Publication Type: Journal Article
UR  - https://doi.org/10.1172/JCI85183
ER  -