Lock, Rebecca <br/><br/>
Cotargeting MNK and MEK kinases induces the regression of NF1-mutant cancers.  [electronic resource] 

 -  The Journal of clinical investigation  06 2016 
 - 2181-90 p.  digital 
<br/><br/> Publication Type: Journal Article 
<br/><br/><label>ISSN: </label>1558-8238 
<br/><br/><label>Standard No.: </label>10.1172/JCI85183  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Anilides--administration & dosage<br/>Animals<br/>Cell Line, Tumor<br/>Genes, Neurofibromatosis 1<br/>Humans<br/>MAP Kinase Kinase Kinases--antagonists & inhibitors<br/>Mechanistic Target of Rapamycin Complex 1<br/>Mice<br/>Multiprotein Complexes--metabolism<br/>Mutation<br/>Nerve Sheath Neoplasms--drug therapy<br/>Neurofibromin 1--genetics<br/>Nucleocytoplasmic Transport Proteins--antagonists & inhibitors<br/>Phosphorylation<br/>Protein Kinase Inhibitors--administration & dosage<br/>Protein Serine-Threonine Kinases--antagonists & inhibitors<br/>Pyridines--administration & dosage<br/>Signal Transduction<br/>TOR Serine-Threonine Kinases--metabolism