TY  - GEN
AU  - Lee,Stanley Chun-Wei
AU  - Dvinge,Heidi
AU  - Kim,Eunhee
AU  - Cho,Hana
AU  - Micol,Jean-Baptiste
AU  - Chung,Young Rock
AU  - Durham,Benjamin H
AU  - Yoshimi,Akihide
AU  - Kim,Young Joon
AU  - Thomas,Michael
AU  - Lobry,Camille
AU  - Chen,Chun-Wei
AU  - Pastore,Alessandro
AU  - Taylor,Justin
AU  - Wang,Xujun
AU  - Krivtsov,Andrei
AU  - Armstrong,Scott A
AU  - Palacino,James
AU  - Buonamici,Silvia
AU  - Smith,Peter G
AU  - Bradley,Robert K
AU  - Abdel-Wahab,Omar
TI  - Modulation of splicing catalysis for therapeutic targeting of leukemia with mutations in genes encoding spliceosomal proteins
SN  - 1546-170X
PY  - 2017///0807
KW  - Anemia, Aplastic
KW  - genetics
KW  - Animals
KW  - Bone Marrow Diseases
KW  - Bone Marrow Failure Disorders
KW  - Bone Marrow Transplantation
KW  - Catalysis
KW  - Cell Line, Tumor
KW  - Epoxy Compounds
KW  - pharmacology
KW  - Flow Cytometry
KW  - Gene Knock-In Techniques
KW  - Hemizygote
KW  - Hemoglobinuria, Paroxysmal
KW  - Humans
KW  - Leukemia, Myeloid, Acute
KW  - Macrolides
KW  - Mice
KW  - Mice, Knockout
KW  - Mutation
KW  - Myelodysplastic Syndromes
KW  - Neoplasm Transplantation
KW  - RNA Splicing
KW  - drug effects
KW  - Reverse Transcriptase Polymerase Chain Reaction
KW  - Serine-Arginine Splicing Factors
KW  - Spliceosomes
N1  - Publication Type: Journal Article
UR  - https://doi.org/10.1038/nm.4097
ER  -