TY - GEN AU - Ou,Sai-Hong Ignatius AU - Weitz,Michael AU - Jalas,John R AU - Kelly,Daniel F AU - Wong,Vanessa AU - Azada,Michele C AU - Quines,Oliver AU - Klempner,Samuel J TI - Alectinib induced CNS radiation necrosis in an ALK+NSCLC patient with a remote (7 years) history of brain radiation SN - 1872-8332 PY - 2017///1218 KW - Adenocarcinoma KW - metabolism KW - Adenocarcinoma of Lung KW - Anaplastic Lymphoma Kinase KW - Brain KW - drug effects KW - Brain Neoplasms KW - drug therapy KW - Carbazoles KW - adverse effects KW - Crizotinib KW - Disease Progression KW - Humans KW - Lung Neoplasms KW - Male KW - Middle Aged KW - Necrosis KW - chemically induced KW - Piperidines KW - Protein Kinase Inhibitors KW - therapeutic use KW - Pyrazoles KW - pharmacology KW - Pyridines KW - Radiation Injuries KW - Receptor Protein-Tyrosine Kinases KW - antagonists & inhibitors KW - Treatment Outcome N1 - Publication Type: Case Reports; Journal Article UR - https://doi.org/10.1016/j.lungcan.2016.03.008 ER -