TY  - GEN
AU  - Wenzel,Sally
AU  - Castro,Mario
AU  - Corren,Jonathan
AU  - Maspero,Jorge
AU  - Wang,Lin
AU  - Zhang,Bingzhi
AU  - Pirozzi,Gianluca
AU  - Sutherland,E Rand
AU  - Evans,Robert R
AU  - Joish,Vijay N
AU  - Eckert,Laurent
AU  - Graham,Neil M H
AU  - Stahl,Neil
AU  - Yancopoulos,George D
AU  - Louis-Tisserand,Mariana
AU  - Teper,Ariel
TI  - Dupilumab efficacy and safety in adults with uncontrolled persistent asthma despite use of medium-to-high-dose inhaled corticosteroids plus a long-acting β2 agonist: a randomised double-blind placebo-controlled pivotal phase 2b dose-ranging trial
SN  - 1474-547X
PY  - 2016///0801
KW  - Administration, Inhalation
KW  - Adult
KW  - Anti-Asthmatic Agents
KW  - administration & dosage
KW  - Antibodies, Monoclonal
KW  - Antibodies, Monoclonal, Humanized
KW  - Asthma
KW  - drug therapy
KW  - Breath Tests
KW  - Budesonide, Formoterol Fumarate Drug Combination
KW  - therapeutic use
KW  - Disease Progression
KW  - Double-Blind Method
KW  - Drug Therapy, Combination
KW  - Female
KW  - Fluticasone-Salmeterol Drug Combination
KW  - Forced Expiratory Volume
KW  - Humans
KW  - Injections, Subcutaneous
KW  - Male
KW  - Middle Aged
KW  - Mometasone Furoate, Formoterol Fumarate Drug Combination
KW  - Nitric Oxide
KW  - analysis
KW  - Treatment Outcome
N1  - Publication Type: Clinical Trial, Phase II; Journal Article; Multicenter Study; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1016/S0140-6736(16)30307-5
ER  -