Blevitt, Jonathan M <br/><br/>
A Single Amino Acid Difference between Mouse and Human 5-Lipoxygenase Activating Protein (FLAP) Explains the Speciation and Differential Pharmacology of Novel FLAP Inhibitors.  [electronic resource] 

 -  The Journal of biological chemistry  Jun 2016 
 - 12724-12731 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1083-351X 
<br/><br/><label>Standard No.: </label>10.1074/jbc.M116.725325  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>5-Lipoxygenase-Activating Protein Inhibitors--chemistry<br/>5-Lipoxygenase-Activating Proteins--chemistry<br/>Amino Acid Sequence<br/>Amino Acid Substitution<br/>Animals<br/>Binding Sites--genetics<br/>Biocatalysis--drug effects<br/>Crystallography, X-Ray<br/>Dogs<br/>Enzyme Assays--methods<br/>Humans<br/>Indoles--chemistry<br/>Mice<br/>Models, Molecular<br/>Molecular Structure<br/>Mutation<br/>Protein Binding<br/>Protein Domains<br/>Quinolines--chemistry<br/>Rats<br/>Sequence Homology, Amino Acid<br/>Species Specificity