TY - GEN AU - Gao,Xiang AU - Ndongo,Marie-Noella AU - Checchio,Tina M AU - Cook,Jack AU - Duncan,Barbara AU - LaBadie,Robert R TI - A randomized, open-label 3-way crossover study to investigate the relative bioavailability and bioequivalence of crushed sildenafil 20 mg tablets mixed with apple sauce, extemporaneously prepared suspension (EP), and intact sildenafil 20 mg tablets in healthy volunteers under fasting conditions SN - 2160-7648 PY - 2018///0122 KW - Administration, Oral KW - Adult KW - Area Under Curve KW - Belgium KW - Biological Availability KW - Cross-Over Studies KW - Drug Compounding KW - Fasting KW - blood KW - Female KW - Fruit KW - Half-Life KW - Healthy Volunteers KW - Humans KW - Male KW - Malus KW - Metabolic Clearance Rate KW - Middle Aged KW - Models, Biological KW - Pharmaceutical Solutions KW - Phosphodiesterase 5 Inhibitors KW - administration & dosage KW - Sildenafil Citrate KW - Tablets KW - Therapeutic Equivalency KW - Young Adult N1 - Publication Type: Comparative Study; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1002/cpdd.146 ER -