Han, Min-Ho <br/><br/>
Polyphenols from Korean prostrate spurge Euphorbia supina induce apoptosis through the Fas-associated extrinsic pathway and activation of ERK in human leukemic U937 cells.  [electronic resource] 

 -  Oncology reports  Jul 2016 
 - 99-107 p.  digital 
<br/><br/> Publication Type: Journal Article 
<br/><br/><label>ISSN: </label>1791-2431 
<br/><br/><label>Standard No.: </label>10.3892/or.2016.4778  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Antineoplastic Agents--isolation & purification<br/>Apoptosis--drug effects<br/>BH3 Interacting Domain Death Agonist Protein--metabolism<br/>Baculoviral IAP Repeat-Containing 3 Protein<br/>Caspase 3--metabolism<br/>Caspase 8--metabolism<br/>Caspase 9--metabolism<br/>Cell Line, Tumor<br/>Cell Proliferation--drug effects<br/>Cytochromes c--metabolism<br/>DNA Fragmentation--drug effects<br/>Enzyme Activation--drug effects<br/>Euphorbia--chemistry<br/>Extracellular Signal-Regulated MAP Kinases--metabolism<br/>G1 Phase Cell Cycle Checkpoints--drug effects<br/>Humans<br/>Inhibitor of Apoptosis Proteins--metabolism<br/>Leukemia--drug therapy<br/>MAP Kinase Signaling System--drug effects<br/>Membrane Potential, Mitochondrial--drug effects<br/>Phosphoinositide-3 Kinase Inhibitors<br/>Phytochemicals--pharmacology<br/>Poly(ADP-ribose) Polymerases--metabolism<br/>Polyphenols--isolation & purification<br/>Republic of Korea<br/>U937 Cells<br/>Ubiquitin-Protein Ligases--metabolism<br/>X-Linked Inhibitor of Apoptosis Protein--metabolism<br/>bcl-2-Associated X Protein--biosynthesis<br/>bcl-Associated Death Protein--biosynthesis