TY - GEN AU - Hanson,Robert L AU - Leti,Fatjon AU - Tsinajinnie,Darwin AU - Kobes,Sayuko AU - Puppala,Sobha AU - Curran,Joanne E AU - Almasy,Laura AU - Lehman,Donna M AU - Blangero,John AU - Duggirala,Ravindranath AU - DiStefano,Johanna K TI - The Arg59Trp variant in ANGPTL8 (betatrophin) is associated with total and HDL-cholesterol in American Indians and Mexican Americans and differentially affects cleavage of ANGPTL3 SN - 1096-7206 PY - 2018///0119 KW - Adult KW - Alleles KW - Amino Acid Substitution KW - Angiopoietin-Like Protein 3 KW - Angiopoietin-Like Protein 8 KW - Angiopoietin-like Proteins KW - genetics KW - Arginine KW - Blood Glucose KW - metabolism KW - Cholesterol, HDL KW - blood KW - Cholesterol, LDL KW - Chromosomes, Human, Pair 19 KW - Cohort Studies KW - Coronary Disease KW - Diabetes Mellitus KW - Female KW - Genome-Wide Association Study KW - Hep G2 Cells KW - Humans KW - Indians, North American KW - Insulin KW - Male KW - Mexican Americans KW - Middle Aged KW - Peptide Hormones KW - Polymorphism, Single Nucleotide KW - Tryptophan N1 - Publication Type: Journal Article UR - https://doi.org/10.1016/j.ymgme.2016.04.007 ER -