Exposure to hypomethylating agent, 5-azacytidine, may improve iCasp9 suicide gene therapy for treating GvHD in allografts. [electronic resource]
- Gene therapy 08 2016
- 664-72 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1476-5462
10.1038/gt.2016.39 doi
Antigens, CD19--genetics Azacitidine--pharmacology Bone Marrow Transplantation--adverse effects Caspase 9--genetics DNA Methylation--drug effects Genes, Transgenic, Suicide--genetics Genetic Therapy--methods Graft vs Host Disease--etiology Humans Jurkat Cells Organic Chemicals--pharmacology Transplantation, Homologous--methods