TY  - GEN
AU  - Maric-Biresev,Jelena
AU  - Hunn,Julia P
AU  - Krut,Oleg
AU  - Helms,J Bernd
AU  - Martens,Sascha
AU  - Howard,Jonathan C
TI  - Loss of the interferon-γ-inducible regulatory immunity-related GTPase (IRG), Irgm1, causes activation of effector IRG proteins on lysosomes, damaging lysosomal function and predicting the dramatic susceptibility of Irgm1-deficient mice to infection
SN  - 1741-7007
PY  - 2016///1014
KW  - Animals
KW  - Autophagy
KW  - Cell Line
KW  - GTP Phosphohydrolases
KW  - analysis
KW  - GTP-Binding Proteins
KW  - Gene Deletion
KW  - Immunity, Innate
KW  - Infections
KW  - genetics
KW  - Lysosomes
KW  - immunology
KW  - Mice
KW  - Mice, Inbred C57BL
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1186/s12915-016-0255-4
ER  -