Maric-Biresev, Jelena <br/><br/>
Loss of the interferon-γ-inducible regulatory immunity-related GTPase (IRG), Irgm1, causes activation of effector IRG proteins on lysosomes, damaging lysosomal function and predicting the dramatic susceptibility of Irgm1-deficient mice to infection.  [electronic resource] 

 -  BMC biology  Apr 2016 
 - 33 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1741-7007 
<br/><br/><label>Standard No.: </label>10.1186/s12915-016-0255-4  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Animals<br/>Autophagy<br/>Cell Line<br/>GTP Phosphohydrolases--analysis<br/>GTP-Binding Proteins--analysis<br/>Gene Deletion<br/>Immunity, Innate<br/>Infections--genetics<br/>Lysosomes--immunology<br/>Mice<br/>Mice, Inbred C57BL