TY - GEN AU - Madan,Babita AU - Patel,Mehul B AU - Zhang,Jiandong AU - Bunte,Ralph M AU - Rudemiller,Nathan P AU - Griffiths,Robert AU - Virshup,David M AU - Crowley,Steven D TI - Experimental inhibition of porcupine-mediated Wnt O-acylation attenuates kidney fibrosis SN - 1523-1755 PY - 2017///0117 KW - Acylation KW - Acyltransferases KW - Animals KW - Benzeneacetamides KW - pharmacology KW - Cell Proliferation KW - drug effects KW - Cells, Cultured KW - Collagen KW - genetics KW - Disease Models, Animal KW - Down-Regulation KW - Enzyme Inhibitors KW - Fibroblasts KW - Fibrosis KW - Inflammation Mediators KW - metabolism KW - Kidney KW - Kidney Diseases KW - etiology KW - Membrane Proteins KW - antagonists & inhibitors KW - Mice, Inbred C57BL KW - Protein Processing, Post-Translational KW - Pyridines KW - Ureteral Obstruction KW - complications KW - Wnt Proteins KW - Wnt Signaling Pathway KW - beta Catenin N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S UR - https://doi.org/10.1016/j.kint.2016.01.017 ER -