Hua, Peiyan <br/><br/>
Costunolide Induces Apoptosis through Generation of ROS and Activation of P53 in Human Esophageal Cancer Eca-109 Cells.  [electronic resource] 

 -  Journal of biochemical and molecular toxicology  Sep 2016 
 - 462-9 p.  digital 
<br/><br/> Publication Type: Journal Article 
<br/><br/><label>ISSN: </label>1099-0461 
<br/><br/><label>Standard No.: </label>10.1002/jbt.21810  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Acetylcysteine--pharmacology<br/>Antineoplastic Agents, Phytogenic--pharmacology<br/>Apoptosis--drug effects<br/>Caspase 3--genetics<br/>Cell Line, Tumor<br/>Cell Proliferation--drug effects<br/>Cell Survival--drug effects<br/>Cyclin-Dependent Kinase Inhibitor p21--agonists<br/>Dose-Response Relationship, Drug<br/>Epithelial Cells--drug effects<br/>Esophagus--drug effects<br/>Free Radical Scavengers--pharmacology<br/>G1 Phase Cell Cycle Checkpoints--drug effects<br/>Gene Expression Regulation<br/>Humans<br/>Membrane Potential, Mitochondrial--drug effects<br/>Mitochondria--drug effects<br/>Poly(ADP-ribose) Polymerases--genetics<br/>Proto-Oncogene Proteins c-bcl-2--antagonists & inhibitors<br/>Reactive Oxygen Species--agonists<br/>Sesquiterpenes--pharmacology<br/>Signal Transduction<br/>Tumor Suppressor Protein p53--agonists<br/>bcl-2-Associated X Protein--agonists