TY - GEN AU - Coleman,David T AU - Gray,Alana L AU - Stephens,Charles A AU - Scott,Matthew L AU - Cardelli,James A TI - Repurposed drug screen identifies cardiac glycosides as inhibitors of TGF-β-induced cancer-associated fibroblast differentiation SN - 1949-2553 PY - 2017///1226 KW - Antineoplastic Agents KW - pharmacology KW - Calcium Signaling KW - drug effects KW - Cancer-Associated Fibroblasts KW - Cardiac Glycosides KW - Cell Differentiation KW - Cell Line, Tumor KW - Cell Shape KW - Cell Survival KW - Dose-Response Relationship, Drug KW - Drug Repositioning KW - Fibronectins KW - metabolism KW - Gene Expression Regulation, Neoplastic KW - Humans KW - Male KW - Myofibroblasts KW - Promoter Regions, Genetic KW - Prostatic Neoplasms KW - drug therapy KW - Smad Proteins KW - genetics KW - Small Molecule Libraries KW - Sodium-Potassium-Exchanging ATPase KW - antagonists & inhibitors KW - Transfection KW - Transforming Growth Factor beta KW - Tumor Microenvironment N1 - Publication Type: Journal Article UR - https://doi.org/10.18632/oncotarget.8609 ER -