TY - GEN AU - Jain,Kanika AU - Suryakumar,Geetha AU - Ganju,Lilly AU - Singh,Shashi Bala TI - Amelioration of ER stress by 4-phenylbutyric acid reduces chronic hypoxia induced cardiac damage and improves hypoxic tolerance through upregulation of HIF-1α SN - 1879-3649 PY - 2017///0605 KW - Altitude KW - Animals KW - Apoptosis KW - drug effects KW - Apoptosis Regulatory Proteins KW - metabolism KW - Chronic Disease KW - Cytoprotection KW - Disease Models, Animal KW - Endoplasmic Reticulum Stress KW - Hypertrophy, Right Ventricular KW - Hypoxia KW - drug therapy KW - Hypoxia-Inducible Factor 1, alpha Subunit KW - Male KW - Molecular Chaperones KW - Myocardium KW - Oxidative Stress KW - Phenylbutyrates KW - pharmacology KW - Protein Carbonylation KW - Proteolysis KW - Rats, Sprague-Dawley KW - Signal Transduction KW - Time Factors KW - Unfolded Protein Response KW - Up-Regulation N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1016/j.vph.2016.03.004 ER -