Jain, Kanika <br/><br/>
Amelioration of ER stress by 4-phenylbutyric acid reduces chronic hypoxia induced cardiac damage and improves hypoxic tolerance through upregulation of HIF-1α.  [electronic resource] 

 -  Vascular pharmacology  08 2016 
 - 36-46 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1879-3649 
<br/><br/><label>Standard No.: </label>10.1016/j.vph.2016.03.004  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Altitude<br/>Animals<br/>Apoptosis--drug effects<br/>Apoptosis Regulatory Proteins--metabolism<br/>Chronic Disease<br/>Cytoprotection<br/>Disease Models, Animal<br/>Endoplasmic Reticulum Stress--drug effects<br/>Hypertrophy, Right Ventricular--metabolism<br/>Hypoxia--drug therapy<br/>Hypoxia-Inducible Factor 1, alpha Subunit--metabolism<br/>Male<br/>Molecular Chaperones--metabolism<br/>Myocardium--metabolism<br/>Oxidative Stress--drug effects<br/>Phenylbutyrates--pharmacology<br/>Protein Carbonylation--drug effects<br/>Proteolysis<br/>Rats, Sprague-Dawley<br/>Signal Transduction--drug effects<br/>Time Factors<br/>Unfolded Protein Response--drug effects<br/>Up-Regulation