TY - GEN AU - Mokhdomi,Taseem A AU - Bukhari,Shoiab AU - Chikan,Naveed Anjum AU - Amin,Asif AU - Wafai,Asrar H AU - Wani,Sajad H AU - Chowdri,Nisar A AU - Qadri,Raies A TI - A novel kinase mutation in VEGFR-1 predisposes its αC-helix/activation loop towards allosteric activation: Atomic insights from protein simulation SN - 1476-5438 PY - 2017///0726 KW - Allosteric Regulation KW - Allosteric Site KW - Colorectal Neoplasms KW - genetics KW - Female KW - Gene Deletion KW - Humans KW - Male KW - Molecular Dynamics Simulation KW - Mutation, Missense KW - Phosphorylation KW - Polymorphism, Single Nucleotide KW - Protein Conformation, alpha-Helical KW - Protein Processing, Post-Translational KW - Vascular Endothelial Growth Factor Receptor-1 KW - chemistry N1 - Publication Type: Journal Article UR - https://doi.org/10.1038/ejhg.2016.26 ER -