TY - GEN AU - Kato,Kazuki AU - Ikeda,Hisako AU - Miyakawa,Shin AU - Futakawa,Satoshi AU - Nonaka,Yosuke AU - Fujiwara,Masatoshi AU - Okudaira,Shinichi AU - Kano,Kuniyuki AU - Aoki,Junken AU - Morita,Junko AU - Ishitani,Ryuichiro AU - Nishimasu,Hiroshi AU - Nakamura,Yoshikazu AU - Nureki,Osamu TI - Structural basis for specific inhibition of Autotaxin by a DNA aptamer SN - 1545-9985 PY - 2017///0629 KW - Animals KW - Aptamers, Nucleotide KW - chemistry KW - Base Sequence KW - Binding Sites KW - Crystallography, X-Ray KW - HEK293 Cells KW - Humans KW - Hydrogen Bonding KW - Hydrophobic and Hydrophilic Interactions KW - Inverted Repeat Sequences KW - Male KW - Mice, Inbred C57BL KW - Models, Molecular KW - Phosphodiesterase Inhibitors KW - Phosphoric Diester Hydrolases KW - Protein Binding KW - Protein Conformation, alpha-Helical KW - Protein Domains N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1038/nsmb.3200 ER -