Structural basis for specific inhibition of Autotaxin by a DNA aptamer. [electronic resource]
- Nature structural & molecular biology 05 2016
- 395-401 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1545-9985
10.1038/nsmb.3200 doi
Animals Aptamers, Nucleotide--chemistry Base Sequence Binding Sites Crystallography, X-Ray HEK293 Cells Humans Hydrogen Bonding Hydrophobic and Hydrophilic Interactions Inverted Repeat Sequences Male Mice, Inbred C57BL Models, Molecular Phosphodiesterase Inhibitors--chemistry Phosphoric Diester Hydrolases--chemistry Protein Binding Protein Conformation, alpha-Helical Protein Domains