TY - GEN AU - Nury,Thomas AU - Zarrouk,Amira AU - Ragot,Kévin AU - Debbabi,Meryam AU - Riedinger,Jean-Marc AU - Vejux,Anne AU - Aubourg,Patrick AU - Lizard,Gérard TI - 7-Ketocholesterol is increased in the plasma of X-ALD patients and induces peroxisomal modifications in microglial cells: Potential roles of 7-ketocholesterol in the pathophysiology of X-ALD SN - 1879-1220 PY - 2017///0710 KW - ATP-Binding Cassette Transporters KW - blood KW - Acyl-CoA Oxidase KW - Adolescent KW - Adrenoleukodystrophy KW - Adult KW - Animals KW - Apoptosis KW - Brain KW - pathology KW - Case-Control Studies KW - Catalase KW - metabolism KW - Cell Survival KW - Child KW - Disease Progression KW - Docosahexaenoic Acids KW - chemistry KW - Glutathione KW - Humans KW - Hydrogen Peroxide KW - Ketocholesterols KW - Linoleic Acid KW - Male KW - Membrane Proteins KW - Mice KW - Microglia KW - cytology KW - Middle Aged KW - Oxidative Stress KW - Peroxisomes KW - Reactive Oxygen Species KW - Repressor Proteins KW - Young Adult KW - alpha-Tocopherol N1 - Publication Type: Journal Article UR - https://doi.org/10.1016/j.jsbmb.2016.03.037 ER -