Piekielna, Justyna <br/><br/>
Redoubling the ring size of an endomorphin-2 analog transforms a centrally acting mu-opioid receptor agonist into a pure peripheral analgesic.  [electronic resource] 

 -  Biopolymers  May 2016 
 - 309-17 p.  digital 
<br/><br/> Publication Type: Journal Article 
<br/><br/><label>ISSN: </label>1097-0282 
<br/><br/><label>Standard No.: </label>10.1002/bip.22846  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Amino Acid Sequence<br/>Analgesics--chemical synthesis<br/>Analgesics, Opioid--chemical synthesis<br/>Animals<br/>Binding Sites<br/>Biological Assay<br/>Blood-Brain Barrier--drug effects<br/>Calcium--metabolism<br/>Cyclization<br/>Dimerization<br/>Humans<br/>Injections, Intraventricular<br/>Male<br/>Mice<br/>Models, Molecular<br/>Molecular Docking Simulation<br/>Oligopeptides--chemical synthesis<br/>Pain--drug therapy<br/>Peptides, Cyclic--chemical synthesis<br/>Protein Binding<br/>Receptors, Opioid, delta--chemistry<br/>Receptors, Opioid, kappa--chemistry<br/>Receptors, Opioid, mu--agonists<br/>Structure-Activity Relationship