Long-Term Exposure of Pancreatic β-Cells to Palmitate Results in SREBP-1C-Dependent Decreases in GLP-1 Receptor Signaling via CREB and AKT and Insulin Secretory Response. [electronic resource]
- Endocrinology 06 2016
- 2243-58 p. digital
Publication Type: Journal Article
1945-7170
10.1210/en.2015-2003 doi
Animals Cell Line Cyclic AMP Response Element-Binding Protein--metabolism Exenatide Glucagon-Like Peptide-1 Receptor--metabolism Humans Insulin--metabolism Insulin-Secreting Cells--drug effects Islets of Langerhans--drug effects Male Mice Mice, Inbred C57BL Palmitates--pharmacology Peptides--pharmacology Proto-Oncogene Proteins c-akt--metabolism Rats Signal Transduction--drug effects Sterol Regulatory Element Binding Protein 1--metabolism Venoms--pharmacology