TY - GEN AU - Koehler,M AU - Donnelly,E T AU - Kalanovic,D AU - Dagher,R AU - Rothenberg,M L TI - Pragmatic randomized clinical trials: a proposal to enhance evaluation of new cancer therapies with early signs of exceptional activity SN - 1569-8041 PY - 2018///0123 KW - Adenine KW - analogs & derivatives KW - Antineoplastic Agents KW - therapeutic use KW - Drug Evaluation KW - methods KW - Humans KW - Neoplasms KW - diagnosis KW - Patient Selection KW - Piperazines KW - Piperidines KW - Pragmatic Clinical Trials as Topic KW - Pyrazoles KW - Pyridines KW - Pyrimidines KW - Randomized Controlled Trials as Topic KW - Research Design KW - trends N1 - Publication Type: Editorial UR - https://doi.org/10.1093/annonc/mdw143 ER -