Yu, Junru <br/><br/>
Role of the Substrate Specificity-Defining Residues of Human SIRT5 in Modulating the Structural Stability and Inhibitory Features of the Enzyme.  [electronic resource] 

 -  PloS one  2016 
 - e0152467 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S. 
<br/><br/><label>ISSN: </label>1932-6203 
<br/><br/><label>Standard No.: </label>10.1371/journal.pone.0152467  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Amino Acids--metabolism<br/>Biocatalysis--drug effects<br/>Calorimetry<br/>Carbazoles--chemistry<br/>Catalytic Domain<br/>Circular Dichroism<br/>Enzyme Stability--drug effects<br/>Humans<br/>Kinetics<br/>Models, Molecular<br/>Mutant Proteins--chemistry<br/>Mutation--genetics<br/>Niacinamide--pharmacology<br/>Protein Denaturation--drug effects<br/>Protein Structure, Secondary<br/>Sirtuin 1--genetics<br/>Sirtuins--antagonists & inhibitors<br/>Structure-Activity Relationship<br/>Substrate Specificity--drug effects<br/>Temperature