Wu, Jing

Investigation of the effect of food and omeprazole on the relative bioavailability of a single oral dose of 240 mg faldaprevir, a selective inhibitor of HCV NS3/4 protease, in an open-label, randomized, three-way cross-over trial in healthy participants. [electronic resource] - The Journal of pharmacy and pharmacology Apr 2016 - 459-66 p. digital

Publication Type: Clinical Trial, Phase I; Journal Article; Randomized Controlled Trial

2042-7158

10.1111/jphp.12538 doi


Administration, Oral
Adult
Aminoisobutyric Acids
Antiviral Agents--administration & dosage
Area Under Curve
Biological Availability
Cross-Over Studies
Female
Food-Drug Interactions
Healthy Volunteers
Hepacivirus--drug effects
Humans
Leucine--analogs & derivatives
Male
Metabolic Clearance Rate
Middle Aged
Oligopeptides--administration & dosage
Omeprazole--administration & dosage
Proline--analogs & derivatives
Protease Inhibitors--administration & dosage
Proton Pump Inhibitors--administration & dosage
Quinolines
Risk Factors
Thiazoles--administration & dosage
Viral Nonstructural Proteins--antagonists & inhibitors
Young Adult