TY  - GEN
AU  - Qin,Xiaoyu
AU  - Wang,Xinxin
AU  - Liu,Feng
AU  - Morris,Laura E
AU  - Wang,Xiaowen
AU  - Jiang,Bin
AU  - Zhang,Yanjie
TI  - Gankyrin activates mTORC1 signaling by accelerating TSC2 degradation in colorectal cancer
SN  - 1872-7980
PY  - 2017///0213
KW  - Animals
KW  - Cell Line, Tumor
KW  - Cell Proliferation
KW  - Colorectal Neoplasms
KW  - enzymology
KW  - Enzyme Activation
KW  - Gene Expression Regulation, Enzymologic
KW  - Gene Expression Regulation, Neoplastic
KW  - Heterografts
KW  - Humans
KW  - Kaplan-Meier Estimate
KW  - Mechanistic Target of Rapamycin Complex 1
KW  - Mice, Inbred BALB C
KW  - Mice, Nude
KW  - Monomeric GTP-Binding Proteins
KW  - metabolism
KW  - Multiprotein Complexes
KW  - Neoplasm Transplantation
KW  - Neuropeptides
KW  - Prognosis
KW  - Proteasome Endopeptidase Complex
KW  - genetics
KW  - Proteolysis
KW  - Proto-Oncogene Proteins
KW  - Ras Homolog Enriched in Brain Protein
KW  - Signal Transduction
KW  - TOR Serine-Threonine Kinases
KW  - Time Factors
KW  - Transfection
KW  - Tuberous Sclerosis Complex 2 Protein
KW  - Tumor Burden
KW  - Tumor Suppressor Proteins
KW  - Up-Regulation
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1016/j.canlet.2016.03.013
ER  -