Jiang, Shanshan

Diosgenin induces ROS-dependent autophagy and cytotoxicity via mTOR signaling pathway in chronic myeloid leukemia cells. [electronic resource] - Phytomedicine : international journal of phytotherapy and phytopharmacology Mar 2016 - 243-52 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1618-095X

10.1016/j.phymed.2016.01.010 doi


Animals
Antineoplastic Agents, Phytogenic--pharmacology
Apoptosis--drug effects
Autophagy--drug effects
Cell Line, Tumor
Diosgenin--pharmacology
Humans
Leukemia, Myelogenous, Chronic, BCR-ABL Positive--pathology
Mice
Reactive Oxygen Species--metabolism
Signal Transduction--drug effects
TOR Serine-Threonine Kinases--metabolism