TY - GEN AU - Chen,Weizao AU - Bardhi,Ariola AU - Feng,Yang AU - Wang,Yanping AU - Qi,Qianqian AU - Li,Wei AU - Zhu,Zhongyu AU - Dyba,Marzena A AU - Ying,Tianlei AU - Jiang,Shibo AU - Goldstein,Harris AU - Dimitrov,Dimiter S TI - Improving the CH1-CK heterodimerization and pharmacokinetics of 4Dm2m, a novel potent CD4-antibody fusion protein against HIV-1 SN - 1942-0870 PY - 2017///1116 KW - AIDS Vaccines KW - chemistry KW - Animals KW - Antibodies, Monoclonal KW - Antibodies, Neutralizing KW - Broadly Neutralizing Antibodies KW - CD4 Antigens KW - HIV-1 KW - immunology KW - Half-Life KW - Humans KW - Immunoglobulin Constant Regions KW - Immunoglobulin Heavy Chains KW - Immunoglobulin kappa-Chains KW - Mice KW - Mice, Inbred C57BL KW - Protein Engineering KW - methods KW - Protein Stability KW - Recombinant Fusion Proteins N1 - Publication Type: Journal Article UR - https://doi.org/10.1080/19420862.2016.1160180 ER -