Improving the CH1-CK heterodimerization and pharmacokinetics of 4Dm2m, a novel potent CD4-antibody fusion protein against HIV-1. [electronic resource]
- mAbs
- 761-74 p. digital
Publication Type: Journal Article
1942-0870
10.1080/19420862.2016.1160180 doi
AIDS Vaccines--chemistry Animals Antibodies, Monoclonal--chemistry Antibodies, Neutralizing--chemistry Broadly Neutralizing Antibodies CD4 Antigens HIV-1--immunology Half-Life Humans Immunoglobulin Constant Regions--chemistry Immunoglobulin Heavy Chains--chemistry Immunoglobulin kappa-Chains--chemistry Mice Mice, Inbred C57BL Protein Engineering--methods Protein Stability Recombinant Fusion Proteins--chemistry