TY - GEN AU - Wang,Suming AU - Blois,Anna AU - El Rayes,Tina AU - Liu,Joyce F AU - Hirsch,Michelle S AU - Gravdal,Karsten AU - Palakurthi,Sangeetha AU - Bielenberg,Diane R AU - Akslen,Lars A AU - Drapkin,Ronny AU - Mittal,Vivek AU - Watnick,Randolph S TI - Development of a prosaposin-derived therapeutic cyclic peptide that targets ovarian cancer via the tumor microenvironment SN - 1946-6242 PY - 2016///1213 KW - Amino Acids KW - metabolism KW - Animals KW - CD36 Antigens KW - Carcinoma, Ovarian Epithelial KW - Cell Death KW - drug effects KW - Cell Line, Tumor KW - Cell Proliferation KW - Cell Survival KW - Cyclization KW - Disease Models, Animal KW - Female KW - Humans KW - Mice, Inbred C57BL KW - Neoplasm Grading KW - Neoplasms, Glandular and Epithelial KW - drug therapy KW - Ovarian Neoplasms KW - Peptides, Cyclic KW - pharmacology KW - Regression Analysis KW - Saposins KW - chemistry KW - Thrombospondin 1 KW - Tissue Array Analysis KW - Tumor Microenvironment KW - Xenograft Model Antitumor Assays N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1126/scitranslmed.aad5653 ER -