Schwerd, Tobias <br/><br/>
Impaired antibacterial autophagy links granulomatous intestinal inflammation in Niemann-Pick disease type C1 and XIAP deficiency with NOD2 variants in Crohn's disease.  [electronic resource] 

 -  Gut  06 2017 
 - 1060-1073 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1468-3288 
<br/><br/><label>Standard No.: </label>10.1136/gutjnl-2015-310382  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Acetylmuramyl-Alanyl-Isoglutamine--metabolism<br/>Adolescent<br/>Adult<br/>Anti-Bacterial Agents--pharmacology<br/>Autophagy--drug effects<br/>Bacteria<br/>Cells, Cultured<br/>Child<br/>Child, Preschool<br/>Chlorpromazine--pharmacology<br/>Crohn Disease--complications<br/>Dopamine Antagonists--pharmacology<br/>Female<br/>Genetic Diseases, X-Linked--genetics<br/>Gentamicins--pharmacology<br/>Granuloma--genetics<br/>Humans<br/>Imidazoles--pharmacology<br/>Leukocytes, Mononuclear<br/>Lysosomes<br/>Macrophages--drug effects<br/>Male<br/>Mutation<br/>Niemann-Pick Disease, Type C--complications<br/>Nod2 Signaling Adaptor Protein--genetics<br/>Protein Kinase Inhibitors--pharmacology<br/>Pyridazines--pharmacology<br/>Receptor-Interacting Protein Serine-Threonine Kinase 2--antagonists & inhibitors<br/>Tumor Necrosis Factor-alpha--metabolism<br/>X-Linked Inhibitor of Apoptosis Protein--deficiency<br/>Young Adult