TY  - GEN
AU  - Warfield,Kelly L
AU  - Plummer,Emily M
AU  - Sayce,Andrew C
AU  - Alonzi,Dominic S
AU  - Tang,William
AU  - Tyrrell,Beatrice E
AU  - Hill,Michelle L
AU  - Caputo,Alessandro T
AU  - Killingbeck,Sarah S
AU  - Beatty,P Robert
AU  - Harris,Eva
AU  - Iwaki,Ren
AU  - Kinami,Kyoko
AU  - Ide,Daisuke
AU  - Kiappes,J L
AU  - Kato,Atsushi
AU  - Buck,Michael D
AU  - King,Kevin
AU  - Eddy,William
AU  - Khaliq,Mansoora
AU  - Sampath,Aruna
AU  - Treston,Anthony M
AU  - Dwek,Raymond A
AU  - Enterlein,Sven G
AU  - Miller,Joanna L
AU  - Zitzmann,Nicole
AU  - Ramstedt,Urban
AU  - Shresta,Sujan
TI  - Inhibition of endoplasmic reticulum glucosidases is required for in vitro and in vivo dengue antiviral activity by the iminosugar UV-4
SN  - 1872-9096
PY  - 2016///1220
KW  - 1-Deoxynojirimycin
KW  - administration & dosage
KW  - Animals
KW  - Antibodies, Viral
KW  - blood
KW  - Antibody-Dependent Enhancement
KW  - drug effects
KW  - Antiviral Agents
KW  - Cells, Cultured
KW  - Chlorocebus aethiops
KW  - Clinical Trials as Topic
KW  - Dengue Virus
KW  - Disease Models, Animal
KW  - Drugs, Investigational
KW  - Endoplasmic Reticulum
KW  - Glycoside Hydrolase Inhibitors
KW  - Humans
KW  - Inhibitory Concentration 50
KW  - Mice
KW  - Monocytes
KW  - virology
KW  - Receptors, Interferon
KW  - deficiency
KW  - Serogroup
KW  - Severe Dengue
KW  - drug therapy
KW  - Vero Cells
KW  - alpha-Glucosidases
KW  - metabolism
N1  - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1016/j.antiviral.2016.03.001
ER  -