Iannazzo, Laura

Routes of Synthesis of Carbapenems for Optimizing Both the Inactivation of L,D-Transpeptidase LdtMt1 of Mycobacterium tuberculosis and the Stability toward Hydrolysis by β-Lactamase BlaC. [electronic resource] - Journal of medicinal chemistry Apr 2016 - 3427-38 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1520-4804

10.1021/acs.jmedchem.6b00096 doi


Bacterial Proteins--antagonists & inhibitors
Carbapenems--chemical synthesis
Humans
Hydrolysis
Kinetics
Mycobacterium tuberculosis--drug effects
Peptidyl Transferases--antagonists & inhibitors
Tuberculosis--drug therapy
beta-Lactamase Inhibitors--chemical synthesis
beta-Lactamases--metabolism