TY  - GEN
AU  - Ren,Xinyi
AU  - Li,Jia
AU  - Xu,Xianxing
AU  - Wang,Chunming
AU  - Cheng,Yuanguo
TI  - IBI302, a promising candidate for AMD treatment, targeting both the VEGF and complement system with high binding affinity in vitro and effective targeting of the ocular tissue in healthy rhesus monkeys
SN  - 1096-0007
PY  - 2017///0613
KW  - Angiogenesis Inhibitors
KW  - pharmacokinetics
KW  - Animals
KW  - Antibodies, Monoclonal, Humanized
KW  - therapeutic use
KW  - Cell Proliferation
KW  - drug effects
KW  - Complement Activation
KW  - Complement Inactivating Agents
KW  - Complement System Proteins
KW  - metabolism
KW  - Human Umbilical Vein Endothelial Cells
KW  - Humans
KW  - Immunoglobulin Fc Fragments
KW  - pharmacology
KW  - Intravitreal Injections
KW  - Macaca mulatta
KW  - Macular Degeneration
KW  - drug therapy
KW  - Recombinant Fusion Proteins
KW  - Vascular Endothelial Growth Factor A
KW  - antagonists & inhibitors
KW  - Vitreous Body
N1  - Publication Type: Journal Article
UR  - https://doi.org/10.1016/j.exer.2016.02.004
ER  -