TY - GEN AU - Nakayama,Robert AU - Zhang,Yi-Xiang AU - Czaplinski,Jeffrey T AU - Anatone,Alex J AU - Sicinska,Ewa T AU - Fletcher,Jonathan A AU - Demetri,George D AU - Wagner,Andrew J TI - Preclinical activity of selinexor, an inhibitor of XPO1, in sarcoma SN - 1949-2553 PY - 2017///1127 KW - Animals KW - Apoptosis KW - drug effects KW - Blotting, Western KW - Cell Line, Tumor KW - Cell Survival KW - Dose-Response Relationship, Drug KW - Drug Screening Assays, Antitumor KW - methods KW - Female KW - G1 Phase Cell Cycle Checkpoints KW - Humans KW - Hydrazines KW - pharmacology KW - Karyopherins KW - antagonists & inhibitors KW - Mice, Nude KW - Proto-Oncogene Proteins c-kit KW - genetics KW - Receptors, Cytoplasmic and Nuclear KW - Reverse Transcriptase Polymerase Chain Reaction KW - Sarcoma KW - drug therapy KW - Signal Transduction KW - Triazoles KW - Xenograft Model Antitumor Assays KW - Exportin 1 Protein N1 - Publication Type: Journal Article UR - https://doi.org/10.18632/oncotarget.7667 ER -