Nakayama, Robert

Preclinical activity of selinexor, an inhibitor of XPO1, in sarcoma. [electronic resource] - Oncotarget Mar 2016 - 16581-92 p. digital

Publication Type: Journal Article

1949-2553

10.18632/oncotarget.7667 doi


Animals
Apoptosis--drug effects
Blotting, Western
Cell Line, Tumor
Cell Survival--drug effects
Dose-Response Relationship, Drug
Drug Screening Assays, Antitumor--methods
Female
G1 Phase Cell Cycle Checkpoints--drug effects
Humans
Hydrazines--pharmacology
Karyopherins--antagonists & inhibitors
Mice, Nude
Proto-Oncogene Proteins c-kit--genetics
Receptors, Cytoplasmic and Nuclear--antagonists & inhibitors
Reverse Transcriptase Polymerase Chain Reaction
Sarcoma--drug therapy
Signal Transduction--drug effects
Triazoles--pharmacology
Xenograft Model Antitumor Assays--methods
Exportin 1 Protein