Diaz, Philippe

Development and Characterization of Novel and Selective Inhibitors of Cytochrome P450 CYP26A1, the Human Liver Retinoic Acid Hydroxylase. [electronic resource] - Journal of medicinal chemistry Mar 2016 - 2579-95 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

1520-4804

10.1021/acs.jmedchem.5b01780 doi


Algorithms
Animals
Cell Line, Tumor
Cytochrome P-450 Enzyme System--drug effects
Drug Design
Drug Resistance
Enzyme Induction
Enzyme Inhibitors--chemical synthesis
Humans
Isoenzymes--antagonists & inhibitors
Kinetics
Liver--drug effects
Rats
Retinoic Acid 4-Hydroxylase
Structure-Activity Relationship
Substrate Specificity
Tretinoin--metabolism